Work

Demonstration of C-peptide Immunoreactivity in Various Body Fluids and Clinical Evaluation of the Determination of Urinary C-peptide Immunoreactivity

Year: 1975

Type: article

Abstract: C-peptide immunoreactivity (CPR) was demonstrated not only in plasma, but in urine, ascites, cerebrospinal fluid and pleural effusion. The concentration of CPR in urine was very high compared with that in the other body fluids and was easy to assay. CPR in urine after glucose administration or tolbutamide injection increased parallel to the change of CPR in plasma and also to that of IRI in normals or diabetics without renal disturbances. The result suggest that the determination of CPR in urine before and after stimulation of insulin secretion could serve as a simple indicator of insulin secretory function of pancreas.

Source: Endocrinologia Japonica

DOI: 10.1507/endocrj1954.22.207

Authors: TOSHIO KANEKO, MASAHIDE MUNEMURA, HIROSHI OKA, TOSHITSUGU ODA, SEIJI SUZUKI, HIROKO YASUDA, NOBORU YANAIHARA, SHINYA NAKAGAWA, KAZUO MAKABE

Institutions: The University of Tokyo, University of Shizuoka, Hitachi General Hospital

Language: English

Topic: Pancreatic function and diabetes

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2071002004

FWCI: 2.71

Cites:

Cited by: 34

Related to: 10