Patterns of multisite pain and associations with risk factors
Year: 2013
Type: article
Study design: Observational Study
Abstract: To explore definitions for multisite pain, and compare associations with risk factors for different patterns of musculoskeletal pain, we analysed cross-sectional data from the Cultural and Psychosocial Influences on Disability (CUPID) study. The study sample comprised 12,410 adults aged 20-59 years from 47 occupational groups in 18 countries. A standardised questionnaire was used to collect information about pain in the past month at each of 10 anatomical sites, and about potential risk factors. Associations with pain outcomes were assessed by Poisson regression, and characterised by prevalence rate ratios (PRRs). Extensive pain, affecting 6-10 anatomical sites, was reported much more frequently than would be expected if the occurrence of pain at each site were independent (674 participants vs 41.9 expected). In comparison with pain involving only 1-3 sites, it showed much stronger associations (relative to no pain) with risk factors such as female sex (PRR 1.6 vs 1.1), older age (PRR 2.6 vs 1.1), somatising tendency (PRR 4.6 vs 1.3), and exposure to multiple physically stressing occupational activities (PRR 5.0 vs 1.4). After adjustment for number of sites with pain, these risk factors showed no additional association with a distribution of pain that was widespread according to the frequently used American College of Rheumatology criteria. Our analysis supports the classification of pain at multiple anatomical sites simply by the number of sites affected, and suggests that extensive pain differs importantly in its associations with risk factors from pain that is limited to only a small number of anatomical sites.
Source: Pain
Authors: David Coggon, Georgia Ntani, Keith T. Palmer, Vanda E. Felli, Raul Harari, Lope H. Barrero, Sarah A. Felknor, David Gimeno, Anna Cattrell, Sergio Vargas-Prada, Matteo Bonzini, Eleni Solidaki, Eda Merisalu, Rima R. Habib, Farideh Sadeghian, M. Masood Kadir, Sudath S.P. Warnakulasuriya, Ko Matsudaira, Busisiwe Nyantumbu, Malcolm R. Sim, Helen Harcombe, Ken Cox, Maria H. Marziale, Leila M. Sarquis, Florencia Harari, Rocio Freire, Natalia Harari, Magda V. Monroy, Leonardo A. Quintana, Marianela Rojas, Eduardo J. Salazar Vega, Clare E. Harris, Consol Serra, Miguel J. Martinez, George Delclos, Fernando G. Benavides, Michele Carugno, Marco M. Ferrario, Angela C. Pesatori, Leda Chatzi, Panos Bitsios, Manolis Kogevinas, Kristel Oha, Tuuli Sirk, Ali Sadeghian, Roshini J. Peiris-John, Nalini Sathiakumar, Rajitha A. Wickremasinghe, Noriko Yoshimura, Helen L. Kelsall, Victor C.W Hoe, Donna M. Urquhart, Sarah Derrett, David McBride, Peter Herbison, Andrew Gray
Institutions: Universitat Pompeu Fabra, Universidade de São Paulo, King's College London, Pontificia Universidad Javeriana, MRC Lifecourse Epidemiology Unit, University of Southampton, Southwest Center for Occupational and Environmental Health, The University of Texas Health Science Center at Houston, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Medical Research Council, University of Insubria, University of Crete, University of Tartu, American University of Beirut, Shahroud University of Medical Sciences, Aga Khan University, University of Sri Jayewardenepura, Kanto Rosai Hospital, National Health Laboratory Service, University of the Witwatersrand, National Institute for Occupational Health, Monash University, University of Otago, Universidade Federal do Paraná, Universidad Nacional, Parc de Salut, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Center for Research in Environmental Epidemiology, National School of Public Health, Municipal Institute for Medical Research, Hospital del Mar Research Institute, North Estonia Medical Centre, Põlva Haigla, Klinikum Leverkusen, University of Auckland, University of Alabama at Birmingham, University of Kelaniya, The University of Tokyo, University of Malaya
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: University of Alabama at Birmingham, University of Alabama, Monash University, Shahroud University of Medical Sciences, Ministerio de Ciencia e Innovación, Università degli Studi dell'Insubria, Pontificia Universidad Javeriana, National Institutes of Health, Medical Research Council, National Health and Medical Research Council, Health Research Council of New Zealand, Fogarty International Center, National Institute of Diabetes and Digestive and Kidney Diseases, Southwest Center for Occupational and Environmental Health
OpenAlex ID: W2076483860