Work

Discovery of 2-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide as a potent and CNS penetrable P2X7 receptor antagonist

Year: 2010

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2010.03.094

Authors: Xiangyang Chen, Betsy Pierce, Win Naing, Margaret L. Grapperhaus, Dennis P. Phillion

Institution: Pfizer (United States)

Language: English

Topic: Adenosine and Purinergic Signaling

Subfield: Physiology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2077549864

FWCI: 2.769

Cites: 18

Cited by: 39

Related to: 10