Year: 2013
Type: article
Abstract: The vertebrate mineralized skeleton is known to have first emerged as an exoskeleton that extensively covered the fossil jawless fish. The evolutionary origin of this exoskeleton has long been attributed to the emergence of the neural crest, but experimental evaluation for this is still poor. Here we determine the embryonic origin of scales and fin rays of medaka (teleost trunk exoskeletons) by applying long-term cell labelling methods, and demonstrate that both tissues are mesodermal in origin. Neural crest cells, however, fail to contribute to these tissues. This result suggests that the trunk neural crest has no skeletogenic capability in fish, instead highlighting the dominant role of the mesoderm in the evolution of the trunk skeleton. This further implies that the role of the neural crest in skeletogenesis has been predominant in the cephalic region from the early stage of vertebrate evolution.
Source: Nature Communications
DOI: 10.1038/ncomms2643
Authors: Atsuko Shimada, Toru Kawanishi, Takuya Kaneko, Hiroki Yoshihara, Tohru Yano, Keiji Inohaya, Masato Kinoshita, Yasuhiro Kamei, Koji Tamura, Hiroyuki Takeda
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $6,990
Awards: Analysis of vertebral column segmentation by the floor plate in medaka, Dorsoventral patterning mechanism in vertebrate late development, Development of temperature sensing fluorescent protein for in vivo thermal imaging induced by infrared laser irradiation to cells, Developmental origin of vertebrate exoskeleton
OpenAlex ID: W2079515751