Work

Finding the genes in genomic DNA

Year: 1998

Type: review

Abstract: Genome sequencing efforts will soon generate hundreds of millions of bases of human genomic DNA containing thousands of novel genes. In the past year, the accuracy of computational gene-finding methods has improved significantly, to the point where a reasonable approximation of the gene structures within an extended genomic region can often be predicted in advance of more detailed experimental studies.

Source: Current Opinion in Structural Biology

DOI: 10.1016/s0959-440x(98)80069-9

Authors: Christopher B Burge, Samuel Karlin

Institutions: Massachusetts Institute of Technology, Stanford University

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $4,360

Funders: National Human Genome Research Institute, National Institute of General Medical Sciences