Induction of lignans and phenolic compounds in cell culture of Linum album by culture filtrate of Fusarium graminearum
Year: 2013
Type: article
Abstract: Cell suspension cultures of Linum album Kotschy ex Boiss. have been reported to produce anticancer podophyllotoxin and its related lignans. In the present study, we investigated the effect of culture filtrate of Fusarium graminearumon growth, and lignan and phenolic compounds in L. album cell culture. After 7 days of pre-culture, the cells were treated with 1% (v/v) of the culture filtrate. Cell growth was reduced, while phodophyllotoxin and lariciresinol production was stimulated reaching a maximum 0.0187 mg/g fresh weight (FW) and 0.0136 mg/g FW 5 days after the treatment, respectively. Also, our results provide evidence that the culture filtrate of F. graminearum can be effective on phenylalanine ammonia-lyase activity and phenolic compounds.
Source: Journal of Plant Interactions
Authors: Jaleh Tahsili, Mozafar Sharifi, Naser Safaie, Sedigheh Esmaeilzadeh-Bahabadi, Mehrdad Behmanesh
Institutions: Tarbiat Modares University, Zabol University
Language: English
Subfield: Plant Science
Domain: Life Sciences
SDG: Zero hunger
Open Access status: bronze
OpenAlex ID: W2082653728