Work

Plasmid-mediated fosfomycin resistance is due to enzymatic modification of the antibiotic

Year: 1985

Type: article

Abstract: The molecular mechanism of plasmid-mediated resistance to fosfomycin is described. The antibiotic was inactivated intracellularly and remained inside the cells. Modification was also obtained from cell extracts and was not energy dependent. The modifying enzyme seems to have sulfhydryl groups in its active center.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.28.1.163

Authors: J Llaneza, C J Villar, J A Salas, J E Suarez, M C Mendoza, C Hardisson

Institution: Universidad de Oviedo

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Microbiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2083000611

FWCI: 2.613

Cites: 10

Cited by: 36

Related to: 10