Work

Response of Immunotherapy to Tumour-TICLs Interactions: A Travelling Wave Analysis

Year: 2014

Type: article

Abstract: There are several cancers for which effective treatment has not yet been identified. Mathematical modelling can nevertheless point out to clinicians tumour invasion properties that should be targeted to mitigate these cancers. We present a travelling wave analysis of a tumour-immune interaction model with immunotherapy. We use the geometric treatment of an apt-phase space to establish the intersection between stable and unstable manifolds. We calculate the minimum wave speed and numerical simulations are performed to support the analytical results.

Source: Abstract and Applied Analysis

DOI: 10.1155/2014/137015

Authors: Joseph Malinzi, Precious Sibanda, Hermane Mambili-Mamboundou

Institution: University of KwaZulu-Natal

Language: English

Topic: Mathematical Biology Tumor Growth

Subfield: Modeling and Simulation

Field: Mathematics

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,130