Work

Real-Time Label-Free Impedimetric Protein Detection Using Interdigitated Gold Microelectrodes and Flow Injection Analysis

Year: 2012

Type: conference-paper

Abstract: Real-time detection of protein binding has been achieved using an impedimetric technique. The fabricated chips boasting interdigitated gold microelectrodes were docked into a microfluidic cell with a sample injection system to guarantee good performance, repeatability and flow injection analysis. Electrochemical impedance spectroscopy (EIS) was carried out to characterize the surface and its response to protein binding using label-free direct capture assays [1] . Real-time measurements of the binding process were performed to monitor the association and dissociation phases of the target-analyte pair.

Source: Procedia Engineering

DOI: 10.1016/j.proeng.2012.09.416

Authors: Unai Eletxigerra, Josu Martínez-Perdiguero, Aritz Juarros, Raquel Bayón, Santos Merino

Institution: Tekniker

Language: English

Topic: Electrochemical sensors and biosensors

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Fundación Centros Tecnológicos Iñaki Goenaga, Eusko Jaurlaritza

OpenAlex ID: W2090104436

FWCI:

Cites: 3

Cited by: 2

Related to: 10