Work

Biological Activity of Rubia cordifolia and Isolation of an Active Principle

Year: 1999

Type: article

Abstract: The present study deals with the isolation of mollugin, furomollugin and dehydro-a-lapchone from the chloroform fraction of Rubia cordifolia (Linn.) roots. Mollugin showed inhibition of passive cutaneous anaphylaxis (PCA) and protection of mast cell degranulation in rats. It also exhibited considerable activity against lymphoid leukemia (P338) in mice. Furomollugin and dehydro-a-lapchone were obtained for the first time from R. cordifolia.

Source: Pharmaceutical Biology

DOI: 10.1076/phbi.37.1.46.6322

Authors: P.P. Gupta, R.C. Srimal, Neeraj Verma, J.S. Tandon

Institution: Central Drug Research Institute

Language: English

Topic: Phytochemistry and biological activity of medicinal plants

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institutes of Health