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Grafting of poly(ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA

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Year: 2009
Type: article
Source: Journal of Controlled Release
DOI: 10.1016/j.jconrel.2009.12.007
Authors: Arihiro Kano, Kenji Moriyama, Takeshi Yamano, Izumi Nakamura, Naohiko Shimada, Atsushi Maruyama
Institutions: Kyushu University, Institute for Materials Chemistry and Engineering, Kyushu University, Japan Science and Technology Agency
Language: English

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Ministry of Education, Culture, Sports, Science and Technology, Japan Society for the Promotion of Science
Awards: PEG-grafted linear cationic polymer for tumor accumulation and cell penetration, Novel nucleic acids nanobiotechnology integrated with materials science
OpenAlex ID: W2093371981
FWCI: 1.418
Cites: 20
Cited by: 69
Related to: 10
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