Work

Effect of Stryphnodendron adstringens (barbatimão) bark on animal models of nociception

Year: 2007

Type: article

Abstract: The antinociceptive activity of the crude extract and fractions of Stryphnodendron adstringens (Martius) Coville (barbatimão) was evaluated. Three experimental models of pain induction were used: abdominal writhing, formalin, and hot plate. The results demonstrated an antinociceptive effect of barbatimão in the experimental models of writhing induced by acetic acid and pain induced by formalin. However, the extracts did not significantly alter latency time on the hot plate in mice. These results suggest that barbatimão extract has a peripheral antinociceptive effect.

Source: Revista Brasileira De Ciencias Farmaceuticas

DOI: 10.1590/s1516-93322007000300015

Authors: Juliana Oliveira de Melo, Tânia Hiromi Endo, Luiz Eduardo Bersani-Amado, Arthur Estivalet Svidzinski, Silmara Baroni, João Carlos Palazzo de Mello, Ciomar Aparecida Bersani-Amado

Institution: Universidade Estadual de Maringá

Language: Portuguese

Topic: Phytochemistry Medicinal Plant Applications

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2096567480

FWCI: 1.647

Cites: 19

Cited by: 26

Related to: 10