OpenAlex | Validation of Surrogate end Points in Multiple Randomized Clinical Trials with Failure Time end Points

Validation of Surrogate end Points in Multiple Randomized Clinical Trials with Failure Time end Points

Work

Year: 2001

Type: article

Abstract: SUMMARY Before a surrogate end point can replace a final (true) end point in the evaluation of an experimental treatment, it must be formally ‘validated’. The validation will typically require large n... more

Source: Journal of the Royal Statistical Society Series C (Applied Statistics)

Authors Tomasz Burzykowski, Geert Molenberghs, Marc Buyse, Helena Geys, Didier Renard

Institutions Transnational University Limburg, International Drug Development Institute (Belgium)

Cites: 30

Cited by: 203

Related to: 10

FWCI: 4.507

Citation percentile (by year/subfield): 96.54

Topic: Statistical Methods in Clinical Trials

Subfield: Statistics and Probability

Field: Mathematics

Domain: Physical Sciences

Open Access status: bronze