Antileishmanial activity of 12-methoxycarnosic acid from Salvia repens Burch. ex Benth. (Lamiaceae)
Year: 2013
Type: article
Abstract: In South Africa, Salvia repens is used traditionally to treat sores, stomach ache and diarrhoea. The high performance liquid chromatography (HPLC)-based activity profiling of S. repens whole plant extract showed an active abietane diterpene, identified as 12-methoxycarnosic acid ( 1 ) which showed antiprotozoal activity against axenically grown Leishmania donovani amastigotes with an IC 50 of 0.75 μM with marginal cytotoxicity against the L6-cells (IC 50 , 17.3 μM).
Source: South African Journal of Botany
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $2,750
OpenAlex ID: W2102902142