Work

Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II.

Year: 1982

Type: article

Abstract: The structures of mycotrienins I and II have been determined mainly by their NMR spectral analysis. Mycotrienins are unique ansamycin antibiotics containing a 21-membered macrocyclic lactam ring and a cyclohexylcarbonyl moiety. The labeling experiments with sodium [1-13C]acetate and sodium [1-13C]propionate revealed that six acetate units and two propionate units were incorporated into the molecule of mycotrienin I.

Source: The Journal of Antibiotics

DOI: 10.7164/antibiotics.35.1467

Authors: MASANORI SUGITA, TETSUO SASAKI, KAZUO FURIHATA, HARUO SETO, NOBORU OTAKE

Institutions: The University of Tokyo, Nisshin Flour Milling Inc. (Japan)

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Applied Microbiology and Biotechnology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2103443301

FWCI: 3.893

Cites: 5

Cited by: 60

Related to: 10