Work

New Constituents from the Leaves of Morinda citrifolia

Year: 2007

Type: article

Abstract: A new iridoid glycoside, citrifoside (1), and a new anthraquinone, 1,5,15-trimethylmorindol (2), together with 24 known compounds, were isolated from the leaves of Morinda citrifolia. The structures of the new compounds were elucidated by spectral data. 1,5,15-Trimethylmorindol (2) did not show significant cytotoxic activity by itself but showed cytotoxicity when combined with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), while citrifoside (1) did not show any activity even with TRAIL.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.55.343

Authors: Junko Takashima, Yoshitaka Ikeda, Kanki Komiyama, Masahiko Hayashi, Akio Kishida, Ayumi Ohsaki

Institutions: Mitsubishi Group (Japan), Kitasato University, Tokyo Medical and Dental University

Language: English

Topic: Morinda citrifolia extract uses

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2103694014

FWCI: 24

Cites: 23

Cited by: 95

Related to: 10