Work

One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate

Year: 2001

Type: article

Abstract: 1,1-Disubstituted-3-(2-phenyl-3H-quinazolin-4-ylidene)thioureas (8) were synthesized in a one pot reaction of N-(2-cyanophenyl)benzimidoyl isothicyanate (3) with secondary amines. The products underwent transamination reactions. Compounds 8a-8g were identified by FTIR, 1H-NMR, 13C-NMR, mass spectroscopy and X-ray crystallography.

Source: Molecules

DOI: 10.3390/60700574

Authors: Walid M. Fathalla, Michal Čajan, Jaromír Marek, Pavel Pazdera

Institution: Masaryk University

Language: English

Topic: Quinazolinone synthesis and applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $3,258

Funder: Grantová Agentura České Republiky