Work

Glycerol Utilization Gene Cluster in Streptomyces clavuligerus

Year: 2009

Type: article

Abstract: The Streptomyces clavuligerus ATCC 27064 glycerol cluster gylR-glpF1K1D1 is induced by glycerol but is not affected by glucose. S. clavuligerus growth and clavulanic acid production are stimulated by glycerol, but this does not occur in a glpK1-deleted mutant. Amplification of glpK1D1 results in transformants yielding larger amounts of clavulanic acid in the wild-type strain and in overproducer S. clavuligerus Gap15-7-30 or S. clavuligerus Delta relA strains.

Source: Applied and Environmental Microbiology

DOI: 10.1128/aem.00181-09

Authors: Sonia Baños, Rosario Pérez-Redondo, Bert Koekman, Paloma Liras

Institutions: Universidad de León, Instituto de Biotecnología de León

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Applied Microbiology and Biotechnology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2105055720

FWCI: 1.168

Cites: 19

Cited by: 27

Related to: 10