Work

EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

Year: 2014

Type: article

Abstract: Nine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo. Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

Source: Chemical Science

DOI: 10.1039/c3sc53056f

Authors: Stephen J. Butler, Laurent Lamarque, Robert Pal, David Parker

Institutions: Durham University, Cisbio (France)

Language: English

Topic: Lanthanide and Transition Metal Complexes

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funder: Engineering and Physical Sciences Research Council

Award: EuroTracker Dyes: Synthesis and Application in Functional Cell Imaging