Year: 2014
Type: article
Abstract: Boron neutron capture therapy (BNCT) is a radiation treatment for cancer that uses charged particles from the 10 B(n, α) 7 Li reaction.The dose from the resulting alpha particles and 7 Li nuclei is called the boron dose, and is the primary dose delivered to tumor cells.Dose to the tumor and surrounding cells during neutron beam irradiation comes not only from the boron dose, but also from dose resulting from the reaction between neutrons and the elements in living tissue, as well as from leakage photons from the reactor core.Those doses other than the boron dose contribute dose not only to tumor cells, but also to healthy tissue.BNCT is performed in consideration of the results of a comprehensive and accurate dose distribution evaluation, but this evaluation is performed only within the localization of the tumor.In this study, we defined the full-body phantom in Monte Carlo code "PHITS".And we evaluated the dose distribution in full-body phantom resulting from BNCT irradiation.Moreover, we also evaluated the radiation shield material that we proposed for effective techniques to reduce the undesirable radiation exposure dose for non-target area during BNCT.
DOI: 10.15669/pnst.4.820
Authors: Kenta Takada, Tomonori Isobe, Hiroaki Kumada, Tetsuya Yamamoto, Koichi Shida, Daisuke Kobayashi, Yutaro Mori, Hideyuki Sakurai, Takeji Sakae
Institutions: University of Tsukuba, University of Tsukuba Hospital
Language: English
Topic: Boron Compounds in Chemistry
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2106340943