Work

A New Chromone, 11-Hydroxy-sec-O-glucosylhamaudol from Ostericum koreanum

Year: 2007

Type: article

Abstract: From the ethyl acetate fraction of the roots of Ostericum koreanum, a new chromone, 11-hydroxy-sec-O-glucosylhamaudol (1) along with the known compounds: four chromones, three coumarins, six phenolic compounds, and three quinic acids were isolated. These compounds were assessed for antioxidant activities in the DPPH radical and superoxide anion radical scavenging assay systems. Among isolates, 4-(2-hydroxy-vinyl)-benzene-1,2-diol (12) showed the most potent DPPH radical scavenging activity (IC(50)=4.80+/-0.62 mug/ml) and superoxide anion radical scavenging activity (IC(50)=11.05+/-0.83 microg/ml) in the xanthine/xanthine oxidase system. The antioxidant activities of 12 were comparable to those of quercetin and luteolin.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.55.1065

Authors: Yeo Jin Park, Hyoung Ja Kim, Sook Ja Lee, Ho-Young Choi, Changbae Jin, Yong Sup Lee

Institutions: Korea Institute of Science and Technology, Hankuk University of Foreign Studies, Kyung Hee University

Language: English

Topic: Phytochemistry and Biological Activities

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Kyung Hee University