Work

Polymer-coated spherical mesoporous silica for pH-controlled delivery of insulin

Year: 2013

Type: article

Abstract: We report a pH-controlled insulin release system to provide an oral administration route. Mesoporous silica was chosen as a drug carrier, and pH-sensitive polymers were coated onto spherical mesocellular foam with pre-adsorbed insulin. We evaluated the insulin release in both acidic and neutral solutions to compare how this system behaves under different pH conditions.

Source: Journal of Materials Chemistry B

DOI: 10.1039/c3tb21494j

Authors: Sae Rom Choi, Dong-Jin Jang, Sanghyun Kim, Sunhyung An, Jinwoo Lee, Euichaul Oh, Jungbae Kim

Institutions: Korea University, Catholic University of Korea, Pohang University of Science and Technology

Language: English

Topic: Mesoporous Materials and Catalysis

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2121001572

FWCI: 2.004

Cites: 29

Cited by: 33

Related to: 10