Work

Simple Assay for 5-Fluorocytosine in the Presence of Amphotericin B

Year: 1976

Type: article

Abstract: A simple method for the measurement of 5-fluorocytosine in the presence of amphotericin B is described. The antifungal activity of amphotericin B is abolished by heating serum at 100 C for 45 min. 5-Fluorocytosine is unaffected by this treatment, and serum levels can be subsequently assayed by either tube dilution or disk diffusion methods.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.9.3.381

Authors: Carol A. Kauffman, Judith A. Carleton, Peter T. Frame

Institutions: Veterans Health Administration, Cincinnati VA Medical Center

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2124394282

FWCI: 4.177

Cites: 13

Cited by: 23

Related to: 10