Regional dispersion of non-syndromic cleft lip withwithout palate Turkish children patients and possible geographical effects
Year: 2012
Type: article
Abstract: Objective: Non-syndromic cleft lip with/without palate (NSCL/P) takes part in multifactorial anomalies. In the present retrospective-descriptive study, we aimed to evaluate the distribution of Turkish children patients with non-syndromic cleft lip with/ without palate according to the geographic regions and analyse the possible geographic and environmental effects which can be considered in the aetiology of the anomaly. Method: Information about the origin, nutritional habits including vitamin intake, occupational and lifetime status were obtained from mothers of NSCL/P patients who gave birth between July 2006 and June 2010. Results: When regional status was investigated, it was found that the eastern parts of Turkey have a relatively higher number of NSCL/P patients than other regions. The ratio of the affected boys to affected girls was found as 154/136. Also, the average age of the mothers at the time of delivery was found to be 24.7. None of the mothers used alcohol or smoked during their lives.Conclusions: Regional differences in nutritional habits and life style have various effects on NSCL/P occurrence, nevertheless more detailed studies are needed to specify the major differences that are responsible.Key words: Cleft lip, cleft palate, nutritional habits, life style, geographical dispersion
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W2129999262