Work

Serological Detection of Capillaria hepatica by Indirect Immunofluorescence Assay

Year: 2000

Type: review

Abstract: In this paper, a serological assay for the detection of antibodies to Capillaria hepatica, a zoonotic parasite, is described. In the past, the only way of detecting Capillaria hepatica was to perform a liver biopsy. The indirect immunofluorescence (IIF) assay, based on liver sections of naturally infected mice and human serum samples, is suitable for detecting early stages of human infections and for screening purposes. No cross-reactivity with other parasitic infections was detected. We have applied the IIF assay to serum samples of 60 employees of the Zoological Garden of Vienna, Schönbrunn, Austria, and found one positive and one questionable sample.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.38.1.431-433.2000

Authors: Martina Juncker-Voss, Heinrich Prosl, Helga Lussy, Ulrike Enzenberg, Herbert Auer, Norbert Nowotny

Institutions: Institute of Parasitology, University of Veterinary Medicine Vienna, Schönbrunner Tiergarten-GmbH, University of Vienna

Language: English

Topic: Parasitic infections in humans and animals

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2135334191

FWCI: 0.181

Cites: 36

Cited by: 61

Related to: 10