Work

Stereoselective Synthesis of Tetrahydronaphthocyclobuta[1,2-d]pyrimidinediones from 5-Fluoro-1,3-dimethyluracil and Naphthalenes

Year: 2005

Type: article

Abstract: Upon UV-irradiation in the presence of piperylene, 5-fluoro-1,3-dimethyluracil (5-FDMU) couples with naphthalenes having either an electron-withdrawing group or an electron-donating group by way of 1,2-cycloaddition via mode selectivity to give the corresponding naphthocyclobutapyrimidines regio- and stereo-selectively.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.53.258

Authors: Kazue Ohkura, Tetsuya Ishihara, Ken-ichi Nishijima, James Michael Diakur, Koh-ichi Seki

Institutions: Health Sciences University of Hokkaido, University of Alberta, Hokkaido University, Central Institute of Isotope Science, Hokkaido University

Language: English

Topic: Organic Chemistry Cycloaddition Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W2136376766

FWCI: 1.523

Cites: 13

Cited by: 12

Related to: 10