Work

Adiponectin and leptin molecular actions and clinical significance in breast cancer.

Year: 2014

Type: article

Abstract: Obesity is an important public health problem and major risk factor for postmenopausal breast cancer. Adipose tissue is the major component involved in the control of the metabolism through energy homeostasis, adipocyte differentiation, insulin sensitivity and the activation of anti-inflammatory metabolic and immune pathways. Leptin and Adiponectin pathways are involved in proliferation process in breast cancer. Current review describes potential relationship between the molecular actions and clinical significance of leptin and adiponectin in breast cancer.

Source: Europe PMC (PubMed Central)

Authors: Mohan Reddy Nalabolu, Kalyani Palasamudram, Kaiser Jamil

Institution: Mahavir Medical Research Centre

Language: English

Topic: Adipokines, Inflammation, and Metabolic Diseases

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2137339787

FWCI: 4.578

Cites: 87

Cited by: 43

Related to: 10