A C‐Linked Disaccharide Analogue of Thomsen–Friedenreich Epitope Induces a Strong Immune Response in Mice
Year: 2012
Type: article
Abstract: Anticancer vaccine: Antigen 2 made out of a tripeptide of β-D-Galp-(1→3)-CH2-α-D-GalNAc-O-Ser and conjugated with keyhole limpet hemocyanin (KLH) protein induced an early and strong immune response (IgG antibodies) in mice. Antigen 3 made out of an α-C-galactoside analogue did not induce such an immune response (see scheme).
Source: Chemistry - A European Journal
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2137449979