Bipolar disorder and alcoholism
Year: 2002
Type: article
Abstract: Bipolar disorder and alcoholism commonly co-occur. Multiple explanations for the relationship between these conditions have been proposed, but this relationship remains poorly understood. Some evidence suggests a genetic link. This comorbidity also has implications for diagnosis and treatment. Alcohol use may worsen the clinical course of bipolar disorder, making it harder to treat. There has been little research on the appropriate treatment for comorbid patients. Some studies have evaluated the effects of valproate, lithium, and naltrexone, as well as psychosocial interventions, in treating alcoholic bipolar patients, but further research is needed. KEY WORDS: comorbidity; manic-depressive psychosis; AODD (alcohol and other drug dependence); alcoholic beverage; prevalence; genetic linkage; disease onset; disease course; diagnosis; drug therapy; lithium; valproate; naltrexone; patient compliance; psychosocial treatment method; literature review Bipolar disorder and alcoholism co-occur at higher than expected rates. That is, they co-occur more often than would be expected by chance and they co-occur more often than do alcoholism and unipolar depression. This article will explore the relationship
Source: Europe PMC (PubMed Central)
Authors: Susan C. Sonne, Kathleen T. Brady
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2139031901