Work

Practical Synthesis of Dirhodium(II) Tetrakis[N-phthaloyl-(S)-tert-leucinate]

Year: 2005

Type: article

Abstract: An efficient and reliable procedure for the preparation of dirhodium(II) tetrakis[N-phthaloyl-(S)-tert-leucinate], Rh2(S-PTTL)(4), a universally effective catalyst for a range of enantioselective carbene transformations, is described. The N-phthaloylation of (S)-tert-leucine by the method of Bose with essentially no racemization is a key to this process.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.53.1366

Authors: Hideyuki Tsutsui, Takumi Abe, Seiichi Nakamura, Masahiro Anada, Shunichi Hashimoto

Institution: Hokkaido University

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: Ministry of Education, Culture, Sports, Science and Technology, Hokkaido University

OpenAlex ID: W2139238708

FWCI: 1.143

Cites: 17

Cited by: 62

Related to: 10