Work

Natural FCoV infection: Cats with FIP exhibit significantly higher viral loads than healthy infected cats

Year: 2005

Type: article

Abstract: Natural feline coronavirus (FCoV) infection has been shown to not only induce intestinal infection with viral shedding, but also systemic infection which either remains without clinical signs or leads to feline infectious peritonitis (FIP). As systemic infection is not the key event in the development of FIP, the question arises as to whether a potential difference in viral load might be of importance. Therefore, the purpose of this study was to quantitatively assess feline coronavirus (FCoV) RNA loads in haemolymphatic tissues of healthy, long-term FCoV-infected cats and cats with FIP. In cats that died from FIP, viral loads were significantly higher, indicating a higher rate of viral replication or a reduced capacity for viral clearance in cats developing and/or suffering from FIP.

Source: Journal of Feline Medicine and Surgery

DOI: 10.1016/j.jfms.2005.07.002

Authors: Anja Kipar, Keith Baptiste, Andreas Barth, Manfred Reinacher

Institutions: University of Liverpool, Justus-Liebig-Universität Gießen

Language: English

Topic: Animal Virus Infections Studies

Subfield: Animal Science and Zoology

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Deutsche Forschungsgemeinschaft