Work

Citric Acid and the RNA World

Year: 2014

Type: article

Abstract: RNA world: The chelation of magnesium ions by citric acid prevents the magnesium-induced aggregation of lipid vesicles and RNA degradation while promoting nonenzymatic RNA oligomerization. These findings suggest a unique role for this simple organic acid in supporting key processes in RNA world organisms.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201400847

Authors: Ulrich F. Müller, Yitzhak Tor

Institution: University of California San Diego

Language: English

Topic: Origins and Evolution of Life

Subfield: Astronomy and Astrophysics

Field: Physics and Astronomy

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Awards: G2273376378, Fluorescent Nucleosides and Oligonucleotides