Work

Site‐Specific Assembly of DNA‐Based Photonic Wires by Using Programmable Polyamides

Year: 2011

Type: article

Abstract: Relay race: The first example of a programmable DNA photonic wire is reported utilizing fluorophore-tethered pyrrole-imidazole polyamides for site-directed fluorophore assembly along a pre-formed DNA duplex (see scheme; PB=Pacific Blue, Cy3=Cyanine 3; orange rectangles=fluorophore). The importance of such control is revealed by efficient energy transport over distances in excess of 27 nm.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201006735

Authors: Wu Su, Markus Schuster, Clive R. Bagshaw, Ulrich Rant, Glenn A. Burley

Institutions: University of Leicester, Technical University of Munich

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: Wellcome Trust, Engineering and Physical Sciences Research Council

Awards: G6324652085, New molecular tools for the 21st century: Molecular design of new DNA-based devices, Design of high-performance magnetic nanovectors for combined diagnostics and therapy