Clinical Characteristics of Pregnancies with a History of Recurrent Miscarriage at a Japanese Perinatal Center
Year: 2015
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: We examined obstetric and fetal/neonatal outcomes in women with a history of recurrent miscarriage. METHODS: We reviewed the obstetric records of all 5,829 nulliparous pregnant women who delivered at #8805;14 weeks' gestation from 2008 through 2013 at our perinatal center. Of these women, 74 had a history of recurrent miscarriage (1.3%). The control population consisted of 4,176 nulliparous women without a history of miscarriage. Demographic information and characteristics of labor were extracted from patient charts. RESULTS: The rate of maternal age #8805;40 years (p<0.01) and the rate of in vitro fertilization use (p<0.01) were higher in women with recurrent miscarriage than in women without miscarriage. Eleven women with recurrent miscarriage (14.9%) were treated with low-dose aspirin with and without subcutaneous heparin. In addition, the rate of cesarean delivery was higher in women with recurrent miscarriage than in women without miscarriage (p=0.02). However, fetal/neonatal outcomes did not differ significantly between the populations. CONCLUSION: The pregnancy of women with a history of recurrent miscarriage is not associated with adverse outcomes at our perinatal center.
Source: Journal of Nippon Medical School
DOI: 10.1272/jnms.82.36
Authors: Kayoko Terada, Kazuho Nakanishi, Shunji Suzuki
Institution: Japanese Red Cross Katsushika Maternity Hospital
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W2145821655