Work

Two Enabling Architectures for DNA‐Templated Organic Synthesis

Year: 2003

Type: article

Abstract: Reactivity can be rationally manipulated in DNA-templated synthesis by altering the design of template architectures: a) The omega (Ω) architecture enables DNA-templated reactions to be encoded by bases distal from the reactive end of the template, regardless of the distance dependence of the reaction. b) The T architecture enables two DNA-templated reactions to take place on a single template in one solution, as illustrated.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.200390351

Authors: Zev J. Gartner, Rozalina Grubina, Christopher T. Calderone, David R. Liu

Institution: Harvard University

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, Alfred P. Sloan Foundation, Searle Scholars Program, National Defense Science and Engineering Graduate, Office of Naval Research

OpenAlex ID: W2147999513

FWCI: 2.829

Cites: 44

Cited by: 107

Related to: 10