Facile one pot microwave enhanced multistep synthesis of novel biologically important scaffold spiro[indole-pyridopyrimidines]
Year: 2005
Type: article
Abstract: A rapid and efficient one pot method for the preparation of novel spiro [indole-pyrido[2,3d]pyrimidines] by the reaction of 'insitu' generated spiro [indole-dihydropyridine] and urea / CS 2 using basic alumina as solid support/ or few drops of DMF as homogenizer under microwave irradiation is reported.Excellent yields (85-89%) and higher purity are obtained in mw enhanced one pot synthesis as compared to conventional procedure which required multistep processes using organic solvents and tedious workups.
Source: ARKIVOC
Authors: Anshu Dandia, Kapil Arya, Sarita Khaturia
Institution: University of Rajasthan
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W2148255387