Polyphasic Identification and Susceptibility to Seven Antifungals of 102 Aspergillus Isolates Recovered from Immunocompromised Hosts in Greece
Year: 2011
Type: article
Abstract: In this study, the first such study in Greece, we used polyphasic identification combined with antifungal susceptibility study to analyze Aspergillus clinical isolates comprising 102 common and rare members of sections Fumigati, Flavi, Terrei, Nidulantes, Nigri, Circumdati, Versicolores, and Usti. High amphotericin B MICs (>2 μg/ml) were found for 17.6% of strains. Itraconazole, posaconazole, and voriconazole MICs of >4 μg/ml were shown in 1%, 5%, and 0% of the isolates, respectively. Anidulafungin, micafungin, and caspofungin minimum effective concentrations (MECs) of ≥2 μg/ml were correspondingly recorded for 4%, 9%, and 33%, respectively, of the strains.
DOI: 10.1128/aac.01491-10
Authors: Michael Arabatzis, Manousos Kambouris, Miltiades Kyprianou, Aikaterini Chrysaki, Maria Foustoukou, Maria Kanellopoulou, Lydia Kondyli, Georgia Kouppari, Chrysa Koutsia-Karouzou, Evangelia Lebessi, Anastasia Pangalis, Efthimia Petinaki, Ageliki Stathi, Eleftheria Trikka-Graphakos, Erriketi Vartzioti, Aliki Vogiatzi, Timoleon-Achilleas Vyzantiadis, Loukia Zerva, Aristea Velegraki
Institutions: National and Kapodistrian University of Athens, Technological Educational Institute of Athens, Children's Hospital Agia Sophia, Panagiotis & Aglaia Kyriakou Children's Hospital, Sismanoglio General Hospital, Hellenic Red Cross, Red Cross Hospital, Simanogleio-Amalia Fleming General Hospital, General Hospital Asklepieio Voulas, University of Thessaly, Thriasio General Hospital of Elefsina, Penteli General Children's Hospital, Aristotle University of Thessaloniki, University General Hospital Attikon
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
Award: G7389588316
OpenAlex ID: W2152138180