Year: 1974
Type: article
Abstract: The first published micrograph of a biological specimen photographed in a high voltage electron microscope (HVEM) appeared in a paper by Van Dorsten et al. in 1947, and it is consequently surprising that the HVEM does not play a greater role in biology 27 yr later. There are various reasons for this. The first prototypes were developed with the aim of enabling the investigator to examine thicker specimens than could be viewed at 100 kV. At the same time, however, the thin-sectioning technique was becoming established and consequently none of these early prototypes led to a commercial instrument (Glauert, 1972). Subsequently, the development of the HVEM was determined more by the needs of metallurgists and
Source: The Journal of Cell Biology
DOI: 10.1083/jcb.63.3.717
Author: Audrey M. Glauert
Institution: University of Cambridge
Language: English
Subfield: Structural Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2154657269
