Cortical involvement in Marchiafava-Bignami disease.
Year: 2005
Type: article
Study design: Case Report
Abstract: Marchiafava-Bignami disease (MBD), a rare complication of chronic alcoholism, is characterized by primary demyelination of the corpus callosum. We report two cases of MBD in which fluid-attenuated inversion recovery (FLAIR) and diffusion-weighted imaging studies revealed symmetrical hyperintense lesions in the cerebral cortex (particularly in the lateral-frontal regions) in addition to the callosal lesions, which suggests an association of diffuse cortical lesions such as Morel's laminar sclerosis with MBD.
Source: PubMed
Authors: Ken Johkura, Makoto Naito, Takayuki Naka
Institution: Hiratsuka Kyosai Hospital
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2162138992