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2'-Amino-.ALPHA.-chloroacetophenone as a Valuable Tool for the Synthesis of Conveniently-Substituted .ALPHA.,.BETA.-Epoxychalcone Derivatives

Year: 2005

Type: article

Abstract: The synthesis of conveniently substituted 2'-amino-alpha,beta-epoxychalcones is described. They were obtained through Darzens condensation of 2'-amino-3',5'-dimethoxy-alpha-chloroacetophenone with benzaldehydes. The latter can undergo different cyclization possibilities and afford a variety of flavonoid analogs with biological potential.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.53.435

Authors: Madeleine Blanc, Maud Martin, Sabrina Okombi, Ahcène Boumendjel

Institutions: Centre National de la Recherche Scientifique, Université Joseph Fourier, Département de Pharmacochimie Moléculaire

Language: English

Topic: Synthesis of Organic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W2170078699

FWCI: 0.191

Cites: 13

Cited by: 4

Related to: 10