Multi-institutional retrospective analysis of learning curves on dosimetry and operation time before and after introduction of intraoperatively built custom-linked seeds in prostate brachytherapy
Year: 2015
Type: article
Study design: Observational Study
Abstract: This multi-institutional retrospective analysis examined learning curves for dosimetric parameters and operation time after introduction of intraoperatively built custom-linked (IBCL) seeds. Data from consecutive patients treated with seed implantation before and after introduction of IBCL seeds (loose seed, n = 428; IBCL seed, n = 426) were collected from 13 centers. Dose-volume histogram parameters, operation times, and seed migration rates were compared before and after introduction of IBCL seeds. At the 1-month CT analysis, no significant differences were seen in dose to 90% of prostate volume between before and after IBCL seed introduction. No learning curve for dosimetry was seen. Prostate and rectal volume receiving at least 150% of prescription dose (V150 and RV150) were higher in the loose-seed group than in the IBCL-seed group. Operation time was extended by up to 10 min when IBCL seeds were used, although there was a short learning curve of about five patients. The percentage of patients with seed migration in the IBCL-seed group was one-tenth that in the loose-seed group. Our study revealed no dosimetric demerits, no learning curve for dosimetry, and a slightly extended operation time for IBCL seeds. A significant reduction in the rate of seed migration was identified in the IBCL-seed group.
Source: Journal of Radiation Research
DOI: 10.1093/jrr/rrv065
Authors: Hiromichi Ishiyama, Takefumi Satoh, Atsunori Yorozu, Shiro Saito, Masaaki Kataoka, Katsuyoshi Hashine, Ryuji Nakamura, Susumu Tanji, Koji Masui, Koji Okihara, Toshio Ohashi, Tetsuo Momma, Manabu Aoki, Kenta Miki, Masako Kato, Masashi Morita, Norihisa Katayama, Yasutomo Nasu, Takashi Kawanaka, Tomoharu Fukumori, Fumitaka Ito, Ryoichi Shiroki, Yuji Baba, Akito Inadome, Yasuo Yoshioka, Hitoshi Takayama, Kazushige Hayakawa
Institutions: Kitasato University, Tokyo Medical Center, National Hospital Organization, Shikoku Cancer Center, Iwate Medical University, Kyoto Prefectural University of Medicine, Keio University, Keio University Hospital, National Hospital Organization Saitama Hospital, Jikei University School of Medicine, SHOWA Medical University, SHOWA Medical University Koto Toyosu Hospital, Okayama University, Tokushima University, Fujita Health University, Japanese Red Cross Kumamoto Hospital, The University of Osaka
Language: English
Subfield: Radiation
Field: Physics and Astronomy
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,430
OpenAlex ID: W2173134352