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Synthesis and Antimicrobial Activity of Pyridines Bearing Thiazoline and Moieties.

Year: 1998

Type: article

Abstract: Two series of new pyridines bearing thiazoline (3a--n) and thiazolidinone (5a--e) moieties were prepared via the cyclization of the corresponding substituted pyridyl thiourea (2a--g) with an appropriately substituted phenacyl bromide or chloroacetic acid, respectively. The antimicrobial activity was determined for representative compounds and most of them showed moderate activity against Gram-positive bacteria.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.46.863

Authors: Hoda Y. HASSAN, Nawal A. El-KOUSSI, Zeinab S. FARGHALY

Institution: Assiut University

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W219068935

FWCI: 0.289

Cites:

Cited by: 33

Related to: 10