Enhanced Ionic Transport Mechanism by Gramicidin A Confined Inside Nanopores Tuned by Atomic Layer Deposition
Year: 2013
Type: article
Abstract: The confinement and the understanding of ion transport through ionic channels when they are confined inside solid-state nanopores smaller than 10 nm remains a challenge. Here we report on the fabrication of biomimetic nanopores with high length (5 μm)/diameter (smaller than 10 nm) ratio obtained using both a track-etched technique and atomic layer deposition on flexible membranes. These membranes present uniform hydrophobic nanopores with a low roughness inside the pores. Gramicidin A is then confined inside nanopores (diameter 10.6, 5.7, and ∼2 nm) leading to the NaCl ionic transport mechanism through a hybrid nanopore similar to the biological ones especially for small diameter (5.7 and ∼2 nm).
DOI: 10.1021/jp403330d
Institutions: École Nationale Supérieure de Chimie de Montpellier, Centre National de la Recherche Scientifique, Institut Européen des Membranes, Institut Charles Gerhardt Montpellier, Centre Hospitalier Universitaire de Besançon, Université de Franche-Comté, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, CEA Marcoule, Institut de Chimie Séparative de Marcoule, École Nationale Supérieure d'Ingénieurs de Caen, Centre de Recherche sur les Ions, les Matériaux et la Photonique
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2233656178