Work

Rapid Reversible Photoswitching of Integrin‐Mediated Adhesion at the Single‐Cell Level

Year: 2015

Type: article

Abstract: Rapid and reversible photoswitching of cell adhesion is achieved by c(RGDfK)-azobenzenes embedded in a poly(ethylene glycol) background on surfaces. The light-induced cis-trans-isomerization of the azobenzene enables switching of cell adhesion on the surface. Reversibility of switching over several consecutive switching cycles is demonstrated by single-cell force spectroscopy.

Source: Advanced Materials

DOI: 10.1002/adma.201504394

Authors: Laith F. Kadem, Michelle Holz, Kristine Grace Suana, Qian Li, Constanze Lamprecht, Rainer Herges, Christine Selhuber‐Unkel

Institution: Christian-Albrechts-Universität zu Kiel

Language: English

Topic: Photochromic and Fluorescence Chemistry

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $6,070

Funders: European Commission, Deutsche Forschungsgemeinschaft, FP7 Ideas: European Research Council

Awards: G319404503, Aerographite as scaffold material for regenerative medicine, Mechanotransduction mediating cell adhesion - towards cell-inspired adaptive materials, G849006543

OpenAlex ID: W2236036261

FWCI: 3.001

Cites: 29

Cited by: 81

Related to: 10