Serum Leptin Düzeylerinin Prostat Kanserli ve Benign Prostat Hiperplazili Hastalarda ve Sağlıklı Kontrollerde (Genç ve Yaşlı) Saptanması
Year: 2004
Type: article
Study design: Observational Study
Abstract: Leptin which is the product of Ob gene derived from adipocytes is a hormone with roles in energy balance, appetite and it has close ties with endocrine as well as metabolic systems. Relationship between leptin and prostate cancer and benign Prostatic hyperplasia (BPH) is currently under investigation. In the present study we investigated whether leptin can be used as a tumor marker for diagnosis and prognosis of prostatic diseases. 23 healthy young volunteers (Group A), 43 healthy aged volunteers (Grup B), 23 patients with PCa (Group C), 23 patients with BPH were recruited into the study. Serum leptin, f-PSA, t-PSA, total cholesterol (Chol), triglyceride , HDL-chol, VLDL-chol, VLDL-chol levels were determined in all groups. When serum leptin and leptin/BMI were analyzed, there was a statistically significant increase in Group B compared to Group C (p
Source: DergiPark (Istanbul University)
Authors: Canatan, Halit, Halifeoğlu, İhsan, Gürsu, M.ferit, Ardıçoğlu, Arslan, Dinçoğlu, Dilnur, Bakan, İbrahim
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2276298638