The Effect of Zingiber Officinale (Ginger) Extract on Blood Pressure and Heart Rate in Healthy Humans
Year: 2014
Type: article
Abstract: Zingiber officinale (ZO) has a long history of traditional use.It contains several constituents such as gingerol, gingerdiol, gingerdione, beta-carotene, capsaicin, caffeic acid and curumin.The present study was undertaken to investigate the effect of consumption of ZO on the heart rate and blood pressure (BP).Subjects for the study comprised of 22 males and 38 females making a total of 60 subjects.The subjects were in 3 groups of 20 each; a Control group (distilled water) and 2 experimental groups (100mg/kg bodyweight and 50mg/kg bodyweight of oral consumption of ZO extract).For each group, three readings were obtained per subject-one before administration, and the other two readings at intervals of 2hrs and 4hrs after consumption of water or ZO.The readings taken comprise of systolic BP, diastolic BP, and the heart rate.Results showed a significant (p<0.05)decrease in all measured parameters 2hrs after ZO administration and a significant (p<0.05)increase in only the systolic BP, 4hrs after ZO administration.It can be concluded that consumption of ZO at doses employed in this study, has a blood pressure lowering effect and this effect is dose-dependent.
Institution: University of Ilorin
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2312373002