Use of B-aminomethyl-p-chlorohydrocinnamic Acid (baclofen) for the Treatment of Cerebral and Spinal Spastic Disorders as an Adjunct to the Rehabilitation of Spastics
Year: 1977
Type: article
Study design: Clinical Trial
Abstract: Baclofen was given to 115 spastic patients whose disorders were secondary to the spinal cord lesion in 57 cases, to the cerebral vascular accident in 18 cases and to the infantile cerebral palsy in 40 cases respectively.Fifteen to thirty mg per day of Baclofen was given for more than two weeks on an average before the evaluation of its effects.Treatment results were evaluated according to the following items:subjective assessment of tightness of muscle, discomfort or pain.objective assessment about alteration in neurological findings, gain or loss in ADL, side effects.Considerable relief of spasticity was noticed both in spinal and cerebral cases and more gain in ADL was also observed particularly in C. P. cases.No serious side effects were encountered.From this study Baclofen was found useful as an adjunct to rehabilitation of the spastics.
Source: リハビリテーション医学 : 日本リハビリテーション医学会誌
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2318079554