Year: 2014
Type: article
Study design: Observational Study
Abstract: AIM: The objective of this study is to estimate the serum magnesium levels in seizure disorders and its possible association with the occurrence of seizures.Blood sample for serum magnesium and other electrolytes (blood glucose, potassium, sodium, calcium, chloride) were taken during the period from the onset of seizures up to 72 hours.DESIGN: The present study is a prospective study carried out at King George Hospital, Visakhapatnam.MATERIALS & METHODS: The present study was carried out on 50 subjects diagnosed as seizures (Generalized Tonic Clonic Seizures) in the age group of 20 to 60 years.The study also included 50 healthy subjects who are matched with cases.STATISTICLE ANALYSIS: The analysis was done using MS Office, Excel Sheet 2007 Software.RESULTS: Serum magnesium levels decreased significantly in patients with seizure disorders when compared to controls.(Mean values for Serum, Magnesium in cases vs. controls 0.964 vs. 2.038 mg/DL.The mean value for serum magnesium is lower when time elapsed after last seizure is shorter.CONCLUSION: Magnesium levels decreased in patients with seizure disorders and the mean values were lower when time elapsed since onset of seizure is shorter indicating the role of magnesium in the pathophysiology of seizures.
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2321750109