Work

A simple approach to fused pyrido[2,3- d ]pyrimidines incorporating khellinone and trimethoxyphenyl moieties as new scaffolds for antibacterial and antifungal agents

Year: 2014

Type: article

Abstract: 2-Amino-3-cyanopyridine is a simple precursor for the synthesis of analogues of Egyptian natural products visnagin and khellin. Fused pyrido[2,3- d ]pyrimidines were prepared under mild reaction conditions. The detailed syntheses and spectroscopic data of the synthesised compounds are reported. Some isolated compounds show antibacterial and antifungal activity.

Source: Heterocyclic Communications

DOI: 10.1515/hc-2013-0199

Authors: Khadiga M. Abu-Zied, Tahia K. Mohamed, Omar K. Al-Duiaj, Magdi E.A. Zaki

Institutions: National Research Centre, Imam Mohammad ibn Saud Islamic University

Language: English

Topic: Synthesis and Characterization of Heterocyclic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $1,808