Year: 1997
Type: article
Study design: Case Report
Abstract: Anorectal malignant melanoma is rare and the prognosis is dismal We report a case of advanced anorectal malignant melanoma with pancreatic metastasis at initial presentation. A 48-year-old woman presented with anal pain and bleeding of 3 months' duration. An elastic soft fist-sized mass was palpated in the lower rectum, and a biopsy specimen was diagnosed as malignant melanoma histologically and immunohistologically. Abdomino perineal resection of the rectum and excision of the pancreatic tumor were performed. The specimen showed a black, solid, soft and fragile tumor, 12×8×5cm, with exophytic growth at the dentate line. The pancreatic tumor was similarly black and solid, and was diagnosed as metastatic melanoma. Adjuvant chemotherapy with cisplatin, dacarvasine and vindesine was performed, followed by immunotherapy with interferon. The patient died 10 months after the operation with early metastasis to the breast and delayed metastasis to the systemic lymph nodes. This case suggests that early dicovery is important for good prognosis of this disease and that aggressive operation should be restrained for its advanced cases.
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2331289201